FDA-Approved Treatments Only
★
★
★
★
Updated: December 5, 2025

Best Weight Loss Injections
Top 10 Providers Compared

Compare America's top-rated GLP-1 providers offering Semaglutide and Tirzepatide. FDA-approved treatments, US-based doctors, and results you can trust.

10
Providers
26%
Max Weight Loss
50
States Covered
FDA-Approved
US Providers
Free Shipping
Online Rx
Our Recommendation

After extensive research, CoreAge Rx stands out as America's best GLP-1 provider with FDA-approved treatments and personalized care.

Get Started with CoreAge Rx
Learn More

Your Journey to Better Health

Weight management involves FDA-approved medications as part of comprehensive, medically supervised plans. These treatments complement diet and exercise.

Understanding Prescription Weight Loss Medications

Weight management is not solely about appearance — it addresses significant health risks like diabetes, hypertension, and cardiovascular disease. Medications target biological factors including appetite regulation and metabolic rate. All medications require qualified healthcare provider supervision.

Potential Benefits

Reduced Appetite

Medications target hunger-related hormones, helping you feel satisfied with smaller portions.

Metabolic Support

Treatments influence glucose metabolism and fat storage, supporting your body's natural processes.

Lifestyle Support

Medications complement dietary and physical activity efforts for comprehensive results.

Important Considerations

Common side effects may include:

Nausea
Headaches
GI discomfort
Injection site reactions
Dizziness

Always discuss risks and benefits with your healthcare provider before starting any medication.

Common Prescription Options

GLP-1 Receptor Agonists

Semaglutide, Liraglutide

Wegovy® and Saxenda® regulate appetite and food intake for individuals meeting specific BMI criteria or with weight-related comorbidities, combined with lifestyle interventions.

Tirzepatide

Mounjaro®

FDA-approved for type 2 diabetes; being studied for weight loss. Off-label weight loss use requires healthcare provider discussion.

Combination Approaches

Zepboundâ„¢

Combines mechanisms targeting multiple hormonal pathways for appetite and metabolism. Requires prescription and professional monitoring.

Ozempic®

Semaglutide

Approved for type 2 diabetes blood sugar control. Weight loss is secondary; not specifically approved for weight management. Off-label use requires licensed provider guidance.

★
★

Taking the Next Steps

Consult licensed healthcare providers to determine if medication is appropriate for you, discuss benefits and risks, and create a tailored treatment plan that fits your lifestyle and health goals.

Frequently Asked Questions

Get answers to common questions about GLP-1 weight loss treatments.

Have more questions? Check out our complete FAQ or contact us.

Important Note

  • •Medications should not be purchased online without valid prescriptions from licensed healthcare providers
  • •Efficacy claims must be based on clinical data and individual patient assessments
  • •Prioritize safety, compliance, and transparency in healthcare services